CAIL
@CAIL Active 2 weeks, 5 days agoMember's groups
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Glycoproteins are prevalent in cellular processes, influencing protein folding, stability, distribution, and function. For instance, glycosylation, the process by which glycans are added to proteins, can enhance […]
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A major point of interest is Fc region glycosylation. The Fc, or fragment crystallizable region of immunoglobulin G (IgG), houses conserved N-linked glycans that are key regulators of immune effector functions such […]
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In addition, the other potential application of lipid nanoparticles is gene therapy. Gene therapy has the potential to treat a broad range of illnesses brought on by genetic mutations. Despite extensive and varied […]
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One key focus in this area is the development of liposome products, which serve as versatile model systems during the research phase. Constructed from phospholipid bilayers, liposomes can be customized in terms of […]
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Glycan Antibody in Diagnostics
Anti-glycan antibodies serve as invaluable biomarkers in diagnosing a spectrum of diseases. For instance, in autoimmune disorders like rheumatoid arthritis and systemic lupus […] -
Sialoside Microarrays
These focus on sialic acids, which are terminal sugars often involved in immune regulation and pathogen recognition. Researchers use these arrays to study how viruses like influenza or […] -
Macrophage reprogramming is a promising therapeutic approach aimed at shifting the balance from a pro-tumor (M2) to an anti-tumor (M1) phenotype. By reprogramming TAMs to adopt an M1-like state, researchers hope to […]
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Macrophages: The Immune System’s Shape-Shifters
Macrophages are known for their remarkable plasticity. Depending on environmental cues, they can polarize into different functional states. The M1 phenotype is p […] -
C1q binding assay for antibody complement activation analysis provides a functional approach to evaluate immune complex interactions and effector potential. Using ELISA or SPR platforms, this assay quantifies the […]
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Custom DNA and peptide aptamers for complement system targeting offer high-affinity molecular tools for immunological research and therapeutic development. These aptamers bind specific complement proteins with […]
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Schwann cell assays for immunology and hemolysis assays provide essential tools for studying immune responses and complement pathway activation. Sourced from species like human, mouse, and rat, these biological […]
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Schwann cell assays for peripheral nerve regeneration studies provide a robust platform to evaluate glial cell function in vitro. These assays assess myelination, neurotrophic factor secretion, and neurite […]
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In vitro microglia phagocytosis assay for neuroinflammation research enables precise evaluation of microglial activity under pathological conditions. Using fluorescence-labeled bioparticles and pH-sensitive […]
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Custom GABAergic neuron differentiation from human stem cells for CNS research enables precise modeling of inhibitory neural circuits. These neurons exhibit region-specific identities and electrophysiological […]
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Neuronal progenitor cells derived from human embryonic stem cells for neurodegenerative research offer a scalable and versatile platform for studying brain disorders. These cells exhibit neurobipolar morphology, […]
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3D in vitro Alzheimer’s disease models using human iPSC-derived neurons offer a physiologically relevant platform to study neurodegeneration. These models replicate key pathological features such as amyloid-beta a […]
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Human M1 macrophages for gene expression studies are derived from screened human peripheral blood and supplied as 1.5 x 10⁶ frozen cells. These pro-inflammatory cells express CD11b, essential for phagocytosis and p […]
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Human M0 macrophages for gene expression studies are isolated from peripheral blood and delivered as 1.5 x 10⁶ cryopreserved cells. These cells express CD11b, a key marker involved in pathogen recognition and c […]
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Human cord blood CD14+ monocytes for macrophage research are positively selected immune cells ideal for studying innate immunity. These monocytes serve as precursors for macrophages and dendritic cells, offering a […]
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BALB/c mouse bone marrow monocytes for research are cryopreserved immune cells isolated from pathogen-free laboratory mice. Delivered as 1 x 10⁷ cells, they are rigorously tested to be free of bacteria, fungi, y […]
