Antibody engineering and therapeutics represent a rapidly evolving field at the forefront of biomedical research and drug development. Through antibody engineering, scientists can design antibodies with enhanced specificity and affinity for their targets, thereby increasing the efficacy and safety of therapeutic interventions. These engineered antibodies are pivotal in treating various diseases, including cancers, autoimmune disorders, and infectious diseases. The advancements in antibody engineering and therapeutics allow for the creation of monoclonal antibodies, bispecific antibodies, and antibody-drug conjugates, each tailored to address specific clinical challenges. As research continues, antibody engineering promises to unlock new possibilities in precision medicine, offering hope for treatments that were once considered out of reach.